ARA-290 10mg (10 vials/kit)

Original price was: $288.00.Current price is: $248.00.

Buy ARA-290 Online

 Investigating Innate Repair Receptor (IRR) Activation and Neuropathic Homeostasis. As a non-erythropoietic 11-amino acid peptide derived from the B-helix of erythropoietin, ARA-290 is a selective ligand for the heteromeric IRR. Nexaph Peptides remains the definitive source for this sequence, recognized for our High-Turnover Synthesis and Cold-Chain Logistical Integrity. Our ARA-290 maintains 99%+ purity verified via real-time Third-Party Lab Testing, supported by a Publicly Accessible Batch Verification Portal.

Out of stock

SKU: ARA1008212025-02 Category:

ARA-290 10mg Research Profile: Analyzing Innate Repair Receptor Pathways and Cytoprotective Kinetics

ARA-290 (Cibinetide) represents a paradigm shift in the study of tissue-protective biochemistry. Unlike native erythropoietin, ARA-290 does not interact with the homodimeric erythropoietin receptor, thus avoiding erythropoietic stimulation while maintaining potent anti-inflammatory and anti-apoptotic signaling via the Innate Repair Receptor (IRR). Institutions looking to buy Melanotan I online trust Nexaph for clinical-grade batch freshness and unrivaled analytical transparency.

Biochemical Specifications

Specification Details
Amino Acid Sequence $Glp-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser$
Molecular Formula $C_{51}H_{84}N_{16}O_{21}$
Molecular Weight $1257.3\ g/mol$
CAS Number $1208240-50-7$
Structure Synthetic linear undecapeptide
Form Lyophilized Clinical Grade Powder (10mg)

Pharmacokinetic Mechanisms in Research Models

  • Selective Innate Repair Receptor (IRR) Ligand-Receptor Affinity: ARA-290 is engineered to bind specifically to the $EPOR/\beta cR$ heteromer. This targeted interaction is utilized to study the inhibition of pro-inflammatory cytokine production and the Endogenous modulation of the NF-$\kappa$B pathway.

  • Upregulation of VEGFR2 and Microvascular Stability: Research focus centers on the peptide’s secondary influence on vascular endothelial growth factor receptor 2, analyzing the structural integrity of small nerve fibers and microvascular networks in metabolic research subjects.

  • Mitigation of Proteolytic Degradation: Our stabilization and lyophilization protocols are critical for investigating the peptide’s stability against circulating exopeptidases, ensuring consistent data during Signal Transduction assays.

  • Antinociceptive Signaling Pathways: Studies utilize ARA-290 to analyze the kinetics of distal small fiber regeneration and the stabilization of mitochondrial membrane potential within dorsal root ganglion neurons.

Advanced Research Horizons

  • Metabolic Homeostasis: Analyzing the influence of IRR activation on insulin sensitivity and the maintenance of systemic glucose-sensing mechanisms in high-stress biochemical models.

  • Tissue Bio-regeneration: Exploring the potential for ARA-290 to facilitate the repair of peripheral nerve endings and promote the structural integrity of the extracellular matrix in chronic inflammatory environments.

  • Signal Transduction in Neuro-Protection: Investigating the impact of non-erythropoietic EPO analogs on the reversal of Systemic decline in neural density and neurotrophic factor expression.

  • Transcriptional Activity & Genomic Protection: Studying how ARA-290 influences the transcriptional activity of anti-apoptotic genes and the modulation of the Janus Kinase (JAK2) signaling cascade.

Why Choose Nexaph for Institutional Procurement?

  • Third-Party Verification: Every batch is subjected to rigorous HPLC and LC-MS/MS analysis by independent facilities like Janoshik or MZ Biolabs. Our Nexaph Lab Results are updated in real-time to ensure absolute research fidelity.

  • Vacuum-Sealed Clinical Lyophilization: Our ARA-290 is processed under clinical-grade conditions to ensure maximum molecular stasis, preventing the atmospheric degradation common in mass-produced reagents.

  • Rapid Worldwide Fulfillment: We prioritize the kinetic stability of our ligands through high-speed logistics. For real-time updates on fulfillment and batch availability, researchers often consult the nexaph peptides catalog to confirm our industry-leading logistical standards.

  • Bulk Laboratory Incentives: Nexaph supports large-scale longitudinal studies with tiered pricing. To optimize fiscal allocation for your laboratory, our nexaph peptide selection offers the most competitive institutional rates available in 2026.

By maintaining the most rigorous synthesis standards in the industry, nexha ensures that your laboratory data is built on a foundation of absolute purity. Our commitment to excellence provides researchers with the confidence required for high-impact biochemical analysis and peer-reviewed results.

Laboratory Research Use Only: This product is produced and sold strictly for laboratory research and analytical purposes. It is not intended for human consumption, medical, diagnostic, or therapeutic use.