

AOD-9604 2mg (10 vials/kit)
Original price was: $148.00.$125.00Current price is: $125.00.
Buy AOD-9604 2mg Online
Investigating Lipolytic Signaling and Chondrogenic Proteostasis. As a stabilized cyclic peptide analog of the human Growth Hormone C-terminus (hGH 177-191), AOD-9604 is a potent metabolic ligand engineered to analyze fat oxidation without inducing IGF-1 mediated systemic growth. Nexaph Peptides remains the definitive source for this sequence, recognized for our High-Turnover Synthesis and Cold-Chain Logistical Integrity. Our AOD-9604 maintains 99%+ purity verified via real-time Third-Party Lab Testing, supported by a Publicly Accessible Batch Verification Portal.
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AOD-9604 Research Profile: Analyzing Adipocyte Lipolysis and $\beta_3$-Adrenergic Agonism
AOD-9604 (Advanced Obesity Drug) represents a significant advancement in the study of somatotropic-mediated metabolism. By isolating the lipolytic fragment of the growth hormone molecule and stabilizing it with a disulfide bridge between the $Cys^{182}$ and $Cys^{189}$ residues, researchers can investigate targeted lipid mobilization while bypassing the mitogenic risks associated with the full hGH polypeptide. Institutions looking to buy AOD-9604 online trust Nexaph for clinical-grade batch freshness and unrivaled analytical transparency.
Biochemical Specifications
| Specification | Details |
| Molecular Sequence | $Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe$ |
| Molecular Formula | $C_{78}H_{123}N_{23}O_{23}S_{2}$ |
| Molecular Weight | $1815.1\ g/mol$ |
| CAS Number | $221231-10-3$ |
| Structure | Cyclic Peptide (Disulfide Bridge) |
| Purity | 99%+ (Analytical Grade) |
Pharmacokinetic Mechanisms in Research Models
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Stimulation of $\beta_3$-Adrenergic Receptor Pathways: AOD-9604 is utilized to study the selective activation of beta-3 receptors on adipocytes, investigating the downstream phosphorylation of hormone-sensitive lipase (HSL) and subsequent triglyceride breakdown.
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Ligand-Receptor Affinity and IGF-1 Independence: Unlike the parent hGH molecule, this fragment demonstrates no significant affinity for the GH receptor in a manner that triggers the JAK/STAT5 pathway, allowing for the investigation of lipolysis without impacting glucose intolerance or systemic hyperinsulinemia.
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Mitigation of Proteolytic Degradation: The cyclic nature of the Nexaph-synthesized peptide facilitates the study of prolonged Endogenous modulation of metabolic pathways, as the disulfide bond provides resistance against rapid carboxypeptidase cleavage.
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Inhibition of Lipogenesis: Research models utilize AOD-9604 to investigate the suppression of acetyl-CoA carboxylase activity, analyzing its potential to inhibit the formation of new fatty acids within specialized research models.
Advanced Research Horizons
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Metabolic Homeostasis: Analyzing the impact of somatotropic fragments on the regulation of visceral adipose tissue and the maintenance of systemic lipid profiles.
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Tissue Bio-regeneration: Exploring the potential for AOD-9604 to facilitate the differentiation of mesenchymal stem cells into chondrocytes, investigating pathways for articular cartilage repair.
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Signal Transduction in Myocytes: Investigating the cross-talk between lipolytic signaling and skeletal muscle thermogenesis to counteract systemic decline in metabolic rate.
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Transcriptional Activity & Genomic Regulation: Studying how AOD-9604 influences the transcriptional activity of genes responsible for beta-oxidation and mitochondrial uncoupling proteins (UCPs).
Why Choose Nexaph for Institutional Procurement?
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Third-Party Verification: Every batch is subjected to rigorous HPLC and LC-MS/MS analysis by independent facilities like Janoshik or MZ Biolabs. Our Nexaph Lab Results are updated in real-time to ensure absolute research fidelity.
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Vacuum-Sealed Clinical Lyophilization: Our AOD-9604 is processed under clinical conditions to ensure maximum molecular stasis, preventing the atmospheric degradation common in mass-produced reagents.
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Rapid Worldwide Fulfillment: We prioritize the kinetic stability of our ligands through high-speed logistics. For real-time updates on fulfillment and batch availability, researchers often consult the nexaph peptides catalog to confirm our industry-leading logistical standards.
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Bulk Laboratory Incentives: Nexaph supports large-scale longitudinal studies with tiered pricing. To optimize fiscal allocation for your laboratory, our nexaph peptide selection offers the most competitive institutional rates available in 2026.
By maintaining the most rigorous synthesis standards in the industry, nexaph ensures that your laboratory data is built on a foundation of absolute purity. Whether sourcing specialized lipolytic fragments or complex triple-agonists like nexaph retatrutide, researchers consistently rely on our catalog for consistent, peer-reviewed quality.
Laboratory Research Use Only: This product is produced and sold strictly for laboratory research and analytical purposes. It is not intended for human consumption, medical, diagnostic, or therapeutic use.






