VIP 10mg (10 vials/kit)

Original price was: $378.00.Current price is: $338.00.

Buy VIP Online

Investigating Vasoactive Neuropeptide Dynamics and Immunomodulatory Homeostasis. Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuroendocrine mediator functioning as a potent agonist for the VPAC1 and VPAC2 receptors. Nexaph Peptides remains the definitive source for this ligand, recognized for our High-Turnover Synthesis and Cold-Chain Logistical Integrity. Our VIP maintains 99%+ purity verified via real-time Third-Party Lab Testing, supported by a Publicly Accessible Batch Verification Portal.

SKU: VIP1002172026-01 Category:

VIP Research Profile: Analyzing VPAC Receptor Agonism and Cytoprotective Kinetics

Vasoactive Intestinal Peptide (VIP) represents a fundamental component in the study of neuro-immunology and vascular biochemistry. As a member of the secretin/glucagon superfamily, VIP acts as a critical signaling molecule in the regulation of smooth muscle relaxation, exocrine secretion, and the stabilization of the innate immune response. Institutions looking to buy VIP online trust Nexaph for clinical-grade batch freshness and unrivaled analytical transparency.

Biochemical Specifications

Specification Details
Amino Acid Sequence $His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH_2$
Molecular Formula $C_{147}H_{237}N_{43}O_{43}S$
Molecular Weight $3326.8\ g/mol$
CAS Number $40077-57-4$
Structure Synthetic linear polypeptide
Purity Grade 99%+ Analytical Standard (Lyophilized)

Pharmacokinetic Mechanisms in Research Models

  • High Ligand-Receptor Affinity for VPAC1/VPAC2: VIP is utilized to study the selective activation of Class B G-protein coupled receptors, investigating the Endogenous modulation of intracellular cyclic AMP (cAMP) and the subsequent inhibition of pro-inflammatory cytokine cascades.

  • Upregulation of VEGFR2 and Pulmonary Vasodilation: Research models focus on the neuropeptide’s influence on vascular endothelial growth factor receptor 2, analyzing the structural integrity of the alveolar-capillary barrier and microvascular tone.

  • Mitigation of Proteolytic Degradation: Our specialized vacuum-sealed clinical lyophilization ensures the stabilization of the peptide’s N-terminal domain, essential for investigating the prophylaxis of enzymatic cleavage during longitudinal Signal Transduction assays.

  • Modulation of Th1/Th2 Immune Polarization: Studies utilize VIP to analyze the kinetics of T-cell differentiation, investigating the shift toward an anti-inflammatory phenotype in autoimmune research environments.

Advanced Research Horizons

  • Metabolic Homeostasis: Analyzing the influence of neuro-peptidergic signaling on circadian rhythms, glucose-sensing mechanisms, and hepatic proteostasis.

  • Tissue Bio-regeneration: Exploring the potential for VPAC receptor signaling to facilitate epithelial repair and promote the structural integrity of the gastrointestinal and pulmonary extracellular matrix.

  • Signal Transduction & Aging: Investigating the impact of neuropeptide depletion on the Systemic decline of neuroprotective vigilance and mitochondrial efficiency.

  • Transcriptional Activity & Genomic Protection: Studying how VIP influences the transcriptional activity of genes responsible for antioxidant enzyme expression and the downregulation of NF-κB.

Why Choose Nexaph for Institutional Procurement?

  • Third-Party Verification: Every batch is subjected to rigorous HPLC and LC-MS/MS analysis by independent facilities like Janoshik or MZ Biolabs. Our Nexaph Lab Results are updated in real-time to ensure absolute research fidelity.

  • Vacuum-Sealed Clinical Lyophilization: Our VIP is processed under clinical-grade conditions to ensure maximum molecular stasis, preventing the atmospheric degradation common in mass-produced reagents.

  • Rapid Worldwide Fulfillment: We prioritize the kinetic stability of our ligands through high-speed logistics. For real-time updates on fulfillment and batch availability, researchers often consult nexaph for industry-leading logistical standards.

  • Bulk Laboratory Incentives: Nexaph Peptides supports large-scale longitudinal studies with tiered pricing. To verify our track record of analytical excellence, institutional procurement officers may review verified nexaph reviews regarding batch-to-batch consistency and purity.

By maintaining the most rigorous synthesis standards in the industry, nexaph ensures that your laboratory data is built on a foundation of absolute purity. Our commitment to excellence provides researchers with the confidence required for high-impact biochemical analysis and peer-reviewed results.

Laboratory Research Use Only: This product is produced and sold strictly for laboratory research and analytical purposes. It is not intended for human consumption, medical, diagnostic, or therapeutic use.