5-Amino-1MQ (Chloride) 50mg (10 Vials/kit)

Original price was: $238.00.Current price is: $198.00.

Buy 5-Amino-1MQ Online

Investigating NNMT Inhibition and Adipocyte Metabolism. As a selective, membrane-permeable small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), 5-Amino-1MQ is a primary substrate for research into metabolic signaling. Nexaph Peptides remains the definitive source for this ligand, recognized for our High-Turnover Synthesis and Cold-Chain Logistical Integrity. Our 5-Amino-1MQ maintains 99%+ purity verified via real-time Third-Party Lab Testing and is supported by a Publicly Accessible Batch Verification Portal.

SKU: AMINOMQ5004162026-03 Category:

5-Amino-1MQ Research Profile: Analyzing NNMT Inhibition and Cellular Energy Dynamics

The study of Nicotinamide N-methyltransferase (NNMT) has become a focal point in molecular biology due to its role in regulating cellular energy expenditure and NAD+ salvage pathways. 5-Amino-1MQ (Chloride) is utilized in laboratory settings to investigate the downstream effects of NNMT suppression on metabolic efficiency. Institutions looking to buy 5-Amino-1MQ online trust Nexaph for clinical-grade batch freshness and unrivaled analytical transparency.

Biochemical Specifications

  • Chemical Name: 5-Amino-1-methylquinolinium chloride

  • Molecular Formula: $C_{10}H_{11}ClN_{2}$

  • Molecular Weight: $194.66\ g/mol$

  • CAS Number: $42464-96-0$

  • Form: High-purity crystalline powder (Chloride salt)

Pharmacokinetic Mechanisms in Research Models

  • Selective NNMT Inhibition: 5-Amino-1MQ acts as a potent inhibitor of the NNMT enzyme, preventing the methylation of nicotinamide and altering the concentration of methyl donors within the cell.

  • Intracellular NAD+ Modulation: By blocking NNMT activity, researchers investigate the preservation of intracellular NAD+ levels, which is a critical cofactor for Ligand-Receptor Affinity and mitochondrial function.

  • Upregulation of GLUT4 Transporters: Studies explore the molecule’s role in the translocation of glucose transporters to the cell membrane, simulating enhanced glucose uptake in skeletal muscle models.

  • Mitigation of Proteolytic Degradation: Research protocols utilize 5-Amino-1MQ to observe the stabilization of protein synthesis pathways and the prevention of muscle tissue systemic decline in aged laboratory models.

Advanced Research Horizons

  • Metabolic Homeostasis: Analyzing the impact of NNMT inhibition on high-fat diet models and its influence on lipid metabolism and adiposity.

  • Tissue Bio-regeneration: Investigating the potential of NNMT inhibitors to facilitate the activation of satellite cells in damaged muscle fibers.

  • Signal Transduction & Epigenetics: Studying how the alteration of S-adenosylmethionine (SAM) levels through NNMT inhibition influences DNA methylation and transcriptional activity.

  • Endogenous Modulation of Energy Flux: Exploring the cross-talk between NNMT activity and the AMPK pathway to regulate global energy expenditure and counteract systemic decline.

Choose Nexaph for Institutional Procurement?

  • Third-Party Verification: Every batch of our Nexaph Peptide products is validated via HPLC and LC-MS/MS by independent labs such as Janoshik or MZ Biolabs. Detailed Nexaph Lab Results are published for every lot to ensure research fidelity.

  • Vacuum-Sealed Clinical Lyophilization: To prevent degradation, our 5-Amino-1MQ is processed under clinical-grade conditions, ensuring a stable, contaminant-free crystalline structure.

  • Rapid Worldwide Fulfillment: We prioritize the kinetic stability of our compounds through high-speed logistics, maintaining the same standards we apply to complex agonists like Nexaph retatrutide.

  • Bulk Laboratory Incentives: Nexaph provides tiered pricing for institutional researchers conducting high-throughput analysis or long-term studies.

By maintaining the most rigorous synthesis standards in the industry, Nexaph ensures that your laboratory data is built on a foundation of absolute purity. When sourcing specialized metabolic inhibitors, researchers consistently rely on the Nexaph Peptide catalog for consistent, peer-reviewed quality.

Laboratory Research Use Only: This product is produced and sold strictly for laboratory research and analytical purposes. It is not intended for human consumption, medical, diagnostic, or therapeutic use.